Normal values

Left ventricle

Men and women, ages 16 to 83, papillary muscles in the LV volume

Pooled weighted mean, SD and limits (mean ± 2 SD) · Kawel-Boehm 2020, Table 5

ParameterMenWomen
nMeanSDLL–ULnMeanSDLL–UL
LVEDV (mL)8321453183–20710641122170–155
LVEDV/BSA (mL/m²)832771547–1071064691245–93
LVESV (mL)832531819–881064391215–64
LVESV/BSA (mL/m²)83229911–47106424710–38
LVSV (mL)832911855–1271064731347–99
LVSV/BSA (mL/m²)77248930–66100445730–59
LVEF (%)83263651–76106466752–79
LVM (g)8321052457–1521064731543–103
LVM/BSA (g/m²)832561036–75106445730–59
LVCO (l/min)4646.11.13.9–8.36324.91.03.0–6.9
LVCI (l/min/m²)4043.20.62.1–4.35722.90.51.9–4.0
LVM/LVEDV (g/mL)7080.70.20.3–1.29440.70.10.4–1.0

Men and women, ages 18 to 83, papillary muscles in the LV mass

Pooled weighted mean, SD and limits (mean ± 2 SD) · Kawel-Boehm 2020, Table 2

ParameterMenWomen
nMeanSDLL–ULnMeanSDLL–UL
LVEDV (mL)4641553095–2154851232278–167
LVEDV/BSA (mL/m²)875791550–108931731250–96
LVESV (mL)464551525–85485431121–64
LVESV/BSA (mL/m²)87529911–4793125710–40
LVSV (mL)4101032161–145432831652–114
LVSV/BSA (mL/m²)701521033–7275849833–64
LVEF (%)87564849–7993166752–79
LVM (g)4641212866–176485832141–125
LVM/BSA (g/m²)805621139–85861491030–68
LVCO (l/min)915.61.13.4–7.8894.50.92.7–6.3
LVCI (l/min/m²)913.00.61.8–4.2892.90.51.9–3.9
LVM/LVEDV (g/mL)2870.70.10.4–0.93270.60.10.3–0.8

Men by age group, papillary muscles in the LV mass

Kawel-Boehm 2020, Table 3

Parameter20–29 years30–39 years40–49 years50–59 years60–69 years
nMean ± SD (LL–UL)nMean ± SD (LL–UL)nMean ± SD (LL–UL)nMean ± SD (LL–UL)nMean ± SD (LL–UL)
LVEDV/BSA (mL/m²)5186 ± 13 (61–112)10581 ± 11 (59–103)11083 ± 14 (55–110)7877 ± 14 (49–105)3478 ± 11 (57–99)
LVESV/BSA (mL/m²)5134 ± 10 (14–53)10530 ± 8 (15–46)11032 ± 9 (13–50)7829 ± 8 (12–45)3430 ± 8 (13–46)
LVSV/BSA (mL/m²)4154 ± 7 (40–68)9351 ± 8 (34–67)10152 ± 8 (36–68)6349 ± 10 (30–69)3448 ± 8 (34–63)
LVEF (%)5160 ± 7 (46–74)10563 ± 7 (49–77)11062 ± 7 (48–76)7863 ± 7 (49–78)3462 ± 7 (48–76)
LVM/BSA (g/m²)5166 ± 11 (44–87)10564 ± 11 (41–86)11064 ± 10 (43–84)7862 ± 10 (42–83)3462 ± 12 (38–87)

Women by age group, papillary muscles in the LV mass

Kawel-Boehm 2020, Table 4

Parameter20–29 years30–39 years40–49 years50–59 years60–69 years
nMean ± SD (LL–UL)nMean ± SD (LL–UL)nMean ± SD (LL–UL)nMean ± SD (LL–UL)nMean ± SD (LL–UL)
LVEDV/BSA (mL/m²)4377 ± 12 (54–100)11077 ± 13 (52–102)12773 ± 12 (50–96)9368 ± 10 (48–89)4168 ± 8 (51–84)
LVESV/BSA (mL/m²)4329 ± 7 (16–43)11029 ± 10 (9–49)12727 ± 7 (12–42)9324 ± 7 (10–38)4125 ± 5 (14–35)
LVSV/BSA (mL/m²)3350 ± 6 (38–63)9249 ± 7 (34–64)11648 ± 8 (32–64)8447 ± 6 (34–59)4144 ± 7 (31–58)
LVEF (%)4362 ± 6 (50–73)11064 ± 6 (52–77)12763 ± 7 (50–76)9365 ± 6 (52–78)4165 ± 6 (53–77)
LVM/BSA (g/m²)4351 ± 11 (29–72)11050 ± 9 (32–68)12749 ± 9 (32–66)9351 ± 10 (31–70)4152 ± 11 (31–74)

Right ventricle

Men and women, ages 20 to 83, papillary muscles in the RV volume

Pooled weighted mean, SD and limits (mean ± 2 SD) · Kawel-Boehm 2020, Table 10

ParameterMenWomen
nMeanpSDpLL–ULgnMeanpSDpLL–ULg
RVEDV (mL)8961663987–2449771222768–176
RVEDV/BSA (mL/m²)1069881753–1231112761448–104
RVESV (mL)896732229–117977501520–80
RVESV/BSA (mL/m²)1069381117–59111230913–48
RVSV (mL)842952643–146924741839–109
RVSV/BSA (mL/m²)955521228–7599948929–66
RVEF (%)106957842–72111260746–74
RVM (g)11736917–549830913–48
RVM/BSA (g/m²)11719410–28981757–28
RVCO (l/min)1555.61.42.8–8.31494.41.02.4–6.4
RVCI (l/min/m²)1553.00.71.5–4.51492.80.61.6–4.0

Men and women, ages 20 to 79, papillary muscles in the RV mass (Maceira 2006)

Mean, SD and limits (mean ± 2 SD) · Kawel-Boehm 2020, Table 9

ParameterMen (n = 60)Women (n = 60)
MeanSDLL–ULMeanSDLL–UL
RVEDV (mL)16327109–2171272479–175
RVEDV/BSA (mL/m²)831358–109741251–97
RVESV (mL)571723–91441513–75
RVESV/BSA (mL/m²)29912–462689–42
RVSV (mL)1061871–141831356–110
RVSV/BSA (mL/m²)54838–7148735–61
RVEF (%)66751–8066752–80
RVM (g)661537–95481126–71
RVM/BSA (g/m²)34720–4828616–40

Men by age group, papillary muscles in the RV volume

Kawel-Boehm 2020, Table 11

Parameter20–29 years30–39 years40–49 years50–59 years
nMean ± SD (LL–UL)nMean ± SD (LL–UL)nMean ± SD (LL–UL)nMean ± SD (LL–UL)*
RVEDV/BSA (mL/m²)5094 ± 15 (63–124)5583 ± 13 (57–109)4981 ± 16 (50–112)5580 ± 16 (48–111)
RVESV/BSA (mL/m²)5044 ± 11 (23–66)5538 ± 8 (22–53)4934 ± 8 (18–49)5535 ± 10 (16–54)
RVSV/BSA (mL/m²)4051 ± 13 (26–77)4346 ± 10 (27–65)4044 ± 11 (23–65)4051 ± 13 (24–78)
RVEF (%)5052 ± 8 (36–69)5555 ± 7 (41–68)4957 ± 8 (40–73)5557 ± 8 (41–74)

Women by age group, papillary muscles in the RV volume

Kawel-Boehm 2020, Table 12

Parameter20–29 years30–39 years40–49 years50–59 years
nMean ± SD (LL–UL)nMean ± SD (LL–UL)nMean ± SD (LL–UL)nMean ± SD (LL–UL)*
RVEDV/BSA (mL/m²)4778 ± 12 (55–101)5176 ± 12 (51–100)4674 ± 14 (46–102)4669 ± 13 (42–95)
RVESV/BSA (mL/m²)4733 ± 12 (10–56)5131 ± 8 (15–48)4629 ± 8 (13–45)4628 ± 8 (11–44)
RVSV/BSA (mL/m²)3746 ± 9 (28–63)3345 ± 12 (22–69)3547 ± 11 (24–69)3742 ± 10 (22–62)
RVEF (%)4756 ± 11 (34–78)5158 ± 9 (39–77)4660 ± 8 (44–76)4661 ± 8 (44–78)

Atria

Left atrial volumes and function

bSSFP; maximal volume at ventricular end-systole · Kawel-Boehm 2020, Table 14

MethodParameterMenWomen
nMeanSDLL–ULnMeanSDLL–UL
Biplane area-length method; LA appendage excludedMax. LA volume (mL)734722031–112841641828–100
Max. LA volume/BSA (mL/m²)734381117–59841391117–61
Min. LA volume (mL)17125106–441462287–38
Min. LA volume/BSA (mL/m²)1711453–241461354–23
LA stroke volume (mL)468441221–67509421021–62
LA stroke volume/BSA (mL/m²)36322610–3443222610–34
LA ejection fraction (%)53462846–7757863848–78
Simpson’s method; LA appendage excludedMax. LA volume (mL)66701540–9969661339–93
Max. LA volume/BSA (mL/m²)6641824–576944828–60
Min. LA volume (mL)6632915–506928715–42
Min. LA volume/BSA (mL/m²)661959–286919411–27
LA ejection fraction (%)6654838–706957645–69
Simpson’s method; LA appendage includedMax. LA volume (mL)256781842–115298661437–94
Max. LA volume/BSA (mL/m²)25640825–5629839725–53
Min. LA volume (mL)19632914–5023824710–38
Min. LA volume/BSA (mL/m²)1961749–252381547–23
LA stroke volume (mL)196471321–73238391019–59
LA stroke volume/BSA (mL/m²)19624612–3623824514–34
LA ejection fraction (%)19659843–7523861747–75

Left atrial diameters and areas

bSSFP · Kawel-Boehm 2020, Table 15

ParameterMenWomen
nMeanSDLL–ULnMeanSDLL–UL
Max. LA area 2Ch (cm²)6021512–306019510–28
Max. LA area 2Ch/BSA (cm²/m²)601126–16601126–16
Max. LA area 3Ch (cm²)6019412–266017410–24
Max. LA area 3Ch/BSA (cm²/m²)601026–14601026–14
Max. LA area 4Ch (cm²)23323513–3217321413–29
Max. LA area 4Ch/BSA (cm²/m²)2331227–161951228–15
Max. LA longitudinal diameter 2Ch (cm)1854.90.73.5–6.21814.60.73.3–5.9
Max. LA longitudinal diameter 2Ch/BSA (cm/m²)1852.60.51.6–3.61812.80.61.6–3.9
Max. LA transverse diameter 2Ch (cm)1264.40.63.2–5.61294.30.53.3–5.2
Max. LA transverse diameter 2Ch/BSA (cm/m²)1262.40.31.7–3.01292.70.32.2–3.2
Max. LA longitudinal diameter 3Ch (cm)665.50.64.2–6.8695.40.74.0–6.7
Max. LA longitudinal diameter 3Ch/BSA (cm/m²)663.20.42.4–4.0693.60.52.7–4.6
Max. LA antero-posterior diameter 3Ch (cm)1853.00.52.0–4.01813.00.52.0–4.0
Max. LA antero-posterior diameter 3Ch/BSA (cm/m²)1851.60.31.0–2.21811.80.41.1–2.5
Max. LA longitudinal diameter 4Ch (cm)1265.80.64.6–7.11295.50.64.2–6.8
Max. LA longitudinal diameter 4Ch/BSA (cm/m²)1263.20.42.3–4.11293.50.52.5–4.4
Max. LA transverse diameter 4Ch (cm)1854.30.53.3–5.31814.10.53.1–5.1
Max. LA transverse diameter 4Ch/BSA (cm/m²)1852.20.31.6–2.91812.50.41.8–3.2

Right atrial volumes and function

Kawel-Boehm 2020, Table 17

MethodParameterMenWomen
NMeanSDLL–ULnMeanSDLL–UL
Biplane area-length method; RA appendage excludedMax. RA volume (mL)66652024–10569531424–81
Max. RA volume/BSA (mL/m²)66381215–6169351016–54
Min. RA volume (mL)6632129–55692379–37
Min. RA volume/BSA (mL/m²)661975–32691556–24
RA ejection fraction (%)6650932–686956938–74
Simpson’s method; RA appendage excludedMax. RA volume (mL)66892246–13269771645–108
Max. RA volume/BSA (mL/m²)66521228–7669511031–71
Min. RA volume (mL)66461614–796935917–53
Min. RA volume/BSA (mL/m²)662799–456923612–35
RA ejection fraction (%)66491029–696954936–72
Simpson’s method; RA appendage includedMax. RA volume (mL)2561082559–158298851849–122
Max. RA volume/BSA (mL/m²)256561232–79298501031–69
Min. RA volume (mL)196501716–84238331111–55
Min. RA volume/BSA (mL/m²)19626810–422382068–32
RA stroke volume (mL)196581626–90238471223–71
RA stroke volume/BSA (mL/m²)19630814–4623828714–42
RA ejection fraction (%)196541034–7423859941–77

Right atrial diameters and areas

bSSFP · Kawel-Boehm 2020, Table 18

ParameterMenWomen
nMeanSDLL–ULnMeanSDLL–UL
Max. RA area 2Ch (cm²)6023415–316021413–29
Max. RA area 2Ch/BSA (cm²/m²)601227–17601227–17
Max. RA area 4Ch (cm²)32421413–3028419312–26
Max. RA area 4Ch/BSA (cm²/m²)3241127–152841228–15
Max. RA longitudinal diameter 2Ch (cm)1265.50.64.2–6.71295.10.63.9–6.3
Max. RA longitudinal diameter 2Ch/BSA (cm/m²)1263.00.42.3–3.71293.20.42.3–4.1
Max. RA transverse diameter 2Ch (cm)1264.20.92.4–6.01294.10.92.4–5.9
Max. RA transverse diameter 2Ch/BSA (cm/m²)1262.30.51.3–3.31292.60.61.5–3.7
Max. RA longitudinal diameter 4Ch (cm)1265.30.64.0–6.61295.10.64.0–6.3
Max. RA longitudinal diameter 4Ch/BSA (cm/m²)1262.90.42.2–3.71293.20.42.4–4.0
Max. RA transverse diameter 4Ch (cm)1264.80.63.7–5.91294.30.63.2–5.4
Max. RA transverse diameter 4Ch/BSA (cm/m²)1262.60.32.1–3.21292.70.32.0–3.4

Aorta and pulmonary arteries

Aortic root, sagittal LVOT bSSFP

Pooled weighted mean, SD and limits · Kawel-Boehm 2020, Table 42

ParameterMenWomen
nMeanSDLL–ULnMeanSDLL–UL
Aortic annulus diameter (mm)29923514–3332820314–27
Aortic annulus diameter/BSA (mm/m²)9112110–148912110–14
Aortic sinus diameter (mm)35932619–4538828517–38
Aortic sinus diameter/BSA (mL/m²)15117213–2114917213–21
Sinotubular junction diameter (mm)29925612–3832821512–31
Sinotubular junction diameter/BSA (mm/m²)9113210–178914210–17

Aortic sinus, cross-sectional bSSFP, systole and diastole

Mean ± SD (limits = mean ± 2 SD) · Kawel-Boehm 2020, Table 38

ParameterMen (n = 60) [mean ± SD (LL–UL) ]Women (n = 60) [mean ± SD (LL–UL)]
SystolicDiastolicSystolicDiastolic
Aortic sinus diameter (cusp-commissure) (mm)34 ± 3 (27–40)32 ± 4 (25–39)30 ± 3 (25–35)28 ± 3 (23–34)
Aortic sinus diameter (cusp-commissure)/BSA (mm/m²)17 ± 2 (14–20)16 ± 2 (13–20)18 ± 2 (14–21)17 ± 2 (13–20)
Aortic sinus diameter (cusp-cusp) (mm)36 ± 4 (28–44)35 ± 4 (27–43)32 ± 3 (26–38)31 ± 3 (24–37)
Aortic sinus diameter (cusp-cusp)/BSA (mm/m²)18 ± 2 (14–22)18 ± 2 (14–22)19 ± 2 (15–23)18 ± 2 (14–22)
Aortic sinus area (cm²)9.2 ± 2.1 (5.0–13.4)8.4 ± 2.0 (4.4–12.4)7.1 ± 1.4 (4.3–9.9)6.5 ± 1.3 (3.9–9.1)
Aortic sinus area/BSA (cm²/m²)4.6 ± 1.0 (2.6–6.6)4.2 ± 0.9 (2.4–6.0)4.2 ± 0.8 (2.6–5.8)3.8 ± 0.8 (2.2–5.4)

Thoracic aorta, luminal diameter at diastole, bSSFP

Mean ± SD (limits = mean ± 2 SD) · Kawel-Boehm 2020, Table 39

LevelMen (n = 208)Mean ± SD (LL–UL)Women (n = 239)Mean ± SD (LL–UL)
Ascending aorta diameter (mm)27 ± 4 (19–34)26 ± 4 (18–33)
Proximal descending aorta diameter (mm)21 ± 3 (15–26)19 ± 2 (15–23)
Distal descending aorta diameter (mm)18 ± 3 (13–23)16 ± 2 (12–20)

Ascending aorta by age, phase contrast (MESA)

Median (5th to 95th percentile) · Kawel-Boehm 2020, Table 40

Age (years)Men (n = 770)Median (5th–95th percentile)Women (n = 842)Median (5th–95th percentile)
Absolute values (mm)
45–5432 (27–37)29 (25–34)
55–6433 (28–41)30 (26–36)
65–7434 (29–41)31 (26–36)
75–8435 (29–41)31 (27–37)
Values indexed to BSA (mm/m²)
45–5416 (13–20)17 (14–21)
55–6417 (14–21)18 (15–22)
65–7418 (14–22)18 (15–22)
75–8419 (15–23)20 (15–28)

Pulmonary arteries

Mean, SD and limits (mean ± 2 SD) · Kawel-Boehm 2020, Table 56

VesselParameterMen (n = 60)Women (n = 60)
MeanSDLL–ULMeanSDLL–UL
MPASystolic diameter (mm)27.42.621–3325.32.619–31
Diastolic diameter (mm)22.92.419–2721.22.117–25
Systolic area (cm²)5.91.13.7–8.15.01.03.0–7.0
Diastolic area (cm²)4.20.82.6–5.83.60.72.2–5.0
Distension (%)42.717.29–7741.815.710–74
RPASystolic diameter (mm)20.22.914–2617.82.414–22
Diastolic diameter (mm)16.62.811–2314.72.211–19
Systolic area (cm²)3.31.01.3–5.32.60.71.2–4.0
Diastolic area (cm²)2.20.80.6–3.81.80.60.6–3.0
Distension (%)50.616.917–8548.214.518–78
LPASystolic diameter (mm)20.12.416–2418.42.114–22
Diastolic diameter (mm)17.32.511–2315.92.012–20
Systolic area (cm²)3.30.81.7–4.92.80.61.6–4.0
Diastolic area (cm²)2.40.71.0–3.82.10.51.1–3.1
Distension (%)35.610.116–5635.210.315–55

T1, ECV, T2 and T2*

Native myocardial T1 and ECV by field strength, vendor and sequence

Pooled weighted mean, SD and limits · Kawel-Boehm 2020, Table 61

ParameterFS (T)VendorTechniquenMeanSDLL–UL
Native T1 time (ms)1.5SiemensMOLLI41797243885–1059
1.5SiemensShMOLLI97196029903–1017
1.5PhilipsMOLLI21598942905–1073
3SiemensMOLLI3011196471103–1290
3SiemensShMOLLI1971130551021–1240
3PhilipsMOLLI201109766964–1230
ECV (%)1.5SiemensMOLLI19926320–32
1.5SiemensShMOLLI29527321–33
1.5PhilipsMOLLI5623317–29
3SiemensMOLLI12926320–32
3SiemensShMOLLI5725220–29
3PhilipsMOLLI10026516–36

Myocardial T2

Mean, SD and limits (mean ± 2 SD) · Kawel-Boehm 2020, Table 62

First author, yearFS (T)VendorTechniquen, male:femaleAge range or mean ± SD (years)MeanSDLL–UL
Wassmuth, 2013 [155]1.5SiemensT2P bSSFP60:1320–7055545–65
Wassmuth, 2013 [155]1.5SiemensFLASH60:1320–7052542–62
Hinojar, 2016 [134]3PhilipsGSE9:3742 ± 1545437–53
Ridouani, 2018 [141]1.5SiemensT2P bSSFP20:2040 ± 1251345–57
Granitz, 2019 [145]1.5PhilipsGSE26:3240 ± 14 (male), 42 ± 13 (female)56350–62
Granitz, 2019 [145]3PhilipsGSE26:3240 ± 14 (male), 42 ± 13 (female)52346–58

T2* grading of myocardial iron at 1.5T

Kawel-Boehm 2020, Table 63

Iron overloadT2* (ms)
Normal> 20
Iron overload10–20
Severe iron overload< 10

Maceira 2006, by sex and age decile

1.5T SSFP, 120 healthy adults, papillary muscles in the LV mass. Mean (95% range) per decile, 20 to 79 years. LV: J Cardiovasc Magn Reson 2006;8:417. RV: Eur Heart J 2006;27:2879.

Petersen 2017 (UK Biobank), by sex and age band

1.5T SSFP, 800 healthy Caucasian adults, papillary muscles in the LV volume. Mean (95% prediction interval) per band, 45 to 74 years. J Cardiovasc Magn Reson 2017;19:18, Tables 6 and 7.

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